IDH2 antibody [GT673] | GeneTex GTX628487 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

IDH2 antibody [GT673]

catalog :

GTX628487

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT673

reactivity :

human

citations: 1

Reference
Liu T, Vachharajani V, Millet P, Bharadwaj M, Molina A, McCall C. Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis. J Biol Chem. 2015;290:396-408 pubmed publisher

product information

Catalog Number :

GTX628487

Product Name :

IDH2 antibody [GT673]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

list of Pubmed id :

25404738

Background :

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq]