HIF1 alpha antibody [GT10211] | GeneTex GTX628480 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

HIF1 alpha antibody [GT10211]

catalog :

GTX628480

quantity :

250.00μl

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT10211

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

GeneTex product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4d	Bourseau Guilmain E, Menard J, Lindqvist E, Indira Chandran V, Christianson H, Cerezo Magaña M, et al. Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells. Nat Commun. 2016;7:11371 pubmed publisher
immunocytochemistry; human; 1:100; fig 5	Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher
	Sharma S, Wang J, Alqassim E, Portwood S, Cortes Gomez E, Maguire O, et al. Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells. Genome Biol. 2019;20:37 pubmed publisher
	Masola V, Bellin G, Vischini G, Dall Olmo L, Granata S, Gambaro G, et al. Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury. Oncotarget. 2018;9:36185-36201 pubmed publisher
	Sharma S, Wang J, Cortes Gomez E, TAGGART R, Baysal B. Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes. Hum Mol Genet. 2017;26:1328-1339 pubmed publisher

product information

Catalog No :

GTX628480

Product Name :

HIF1 alpha antibody [GT10211]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

250.00μl

List Price :

299 USD

list of Pubmed id :

25438054

Clone :

GT10211

Isotype :

IgG2a

Product Description :

Mouse Monoclonal antibody to HIF1 alpha (hypoxia-inducible factor 1-alpha)

CrossReactivity :

Background :

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]

Buffer :

PBS

Uses :

ICC/IF, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

HIF1 alpha antibody [GT10211] detects HIF1 alpha protein by western blot analysis. Un-treated (-) and treated (+, 500 μM CoCl2 treatment for 24hr) HeLa whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with HIF1 alpha antibody [GT10211] (GTX628480) at a dilution of 1:500.

more info or order :

GeneTex product webpage