c-Myc antibody [GT168] | GeneTex GTX628459 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

c-Myc antibody [GT168]

catalog :

GTX628459

quantity :

200.00μl

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT168

reactivity :

human

application :

western blot, immunoprecipitation, FACS, immunohistochemistry - paraffin section

product information

Catalog No :

GTX628459

Product Name :

c-Myc antibody [GT168]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

200.00μl

List Price :

299 USD

Clone :

GT168

Isotype :

IgG1

Product Description :

Mouse Monoclonal antibody [GT168] to c-Myc (v-myc myelocytomatosis viral oncogene homolog (avian))

CrossReactivity :

Background :

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Buffer :

PBS

Uses :

FACS, IHC-P, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

c-Myc antibody [GT168] antibody (GTX628459) detects c-Myc protein by flow cytometry analysis. Sample: NT2D1 cell. Black: Unlabelled sample was also used as a control. Red: c-Myc antibody [GT168] antibody (GTX628459) dilution: 1:50. Acquisition of >20,000 events were collected using Argon ion laser (488nm) and 525/30 bandpass filter.

Image Legend_5 :

Immunoprecipitation of c-Myc protein from HeLa nuclear extracts using 5 μg of c-Myc antibody [GT168] (GTX628459). Western blot analysis was performed using c-Myc antibody [GT168] (GTX628459). EasyBlot anti-Mouse IgG (GTX221667-01) was used as a secondary reagent.