Nanog antibody [GT3312] | GeneTex GTX627421 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Nanog antibody [GT3312]

catalog :

GTX627421

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

citations: 8

Reference
Yang C, Lee W, Cheng H, Chung C, Mi F, Lin C. The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells. Chem Biol Interact. 2019;302:28-35 pubmed publisher
Ko C, Lin C, Chuang J, Chang W, Hsu T. MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance. Mol Neurobiol. 2018;55:3211-3223 pubmed publisher
Chang K, Huang C, Hsu T, Hsu C, Liu J, Chuang C, et al. Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma. Biochem Biophys Res Commun. 2017;493:14-19 pubmed publisher
Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn L, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017;114:1033-1038 pubmed publisher
Huang T, Ping Y, Wang A, Ke C, Fang W, Huang K, et al. The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis. Oncotarget. 2015;6:18012-26 pubmed
Wang A, Huang T, Hsu K, Huang K, Fang W, Yang M, et al. Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis. Oncotarget. 2014;5:5002-16 pubmed
Liu K, Yo Y, Huang R, Wang Y, Liao Y, Huang T, et al. Ovarian cancer stem-like cells show induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor. Oncotarget. 2013;4:2366-82 pubmed
Huang A, Chen M, Huang S, Kao C, Lai H, Chan J. CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1?/CXCR4 axis. Mol Cancer. 2013;12:115 pubmed publisher

product information

Catalog Number :

GTX627421

Product Name :

Nanog antibody [GT3312]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

list of Pubmed id :

24094005,28096337,26041881,28478507,24970812,24280306,28939040

Background :

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation.