product summary
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company name :
GeneTex
product type :
antibody
product name :
GAPDH antibody [GT239]
catalog :
GTX627408
quantity :
100.00μl
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GT239
reactivity :
root, human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 83
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3b
Taura M, Song E, Ho Y, Iwasaki A. Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat. Proc Natl Acad Sci U S A. 2019;116:2282-2289 pubmed publisher
  • western blot; root; loading ...; fig 5b
Ashok A, Karmakar S, Chandel R, Ravikumar R, Dalal S, Kong Q, et al. Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission. Exp Eye Res. 2018;175:1-13 pubmed publisher
  • western blot; human; 1:5000; fig 2
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, et al. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016;7:12347 pubmed publisher
  • western blot; human; 1:5000; fig 1h
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
  • western blot; mouse; fig 2
Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher
  • western blot; human; fig 4
Tsai K, Leung C, Lo Y, Chen T, Chan W, Yu S, et al. Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer. Sci Rep. 2016;6:28176 pubmed publisher
  • western blot; human; fig s7
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
  • western blot; human; 1:2000
Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y, et al. An essential receptor for adeno-associated virus infection. Nature. 2016;530:108-12 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig 2
Wu J, Chen Y, Kuo C, Wenshin Yu H, Chen Y, Chiou A, et al. Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration. Sci Rep. 2015;5:18476 pubmed publisher
  • western blot; human; fig 2
Paret C, Simon P, Vormbrock K, Bender C, Kölsch A, Breitkreuz A, et al. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer. Oncotarget. 2015;6:25356-67 pubmed publisher
  • western blot; human; fig 1e
Shi J, Liu Y, Xu X, Zhang W, Yu T, Jia J, et al. Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling. Mol Cell Biol. 2015;35:3301-11 pubmed publisher
  • western blot; mouse; 1:1000
Kubli D, Cortez M, Moyzis A, Najor R, Lee Y, Gustafsson Ã. PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes. PLoS ONE. 2015;10:e0130707 pubmed publisher
  • western blot; human; 1:5000; fig 4
Kohl S, Zobor D, Chiang W, Weisschuh N, Staller J, González Menéndez I, et al. Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. Nat Genet. 2015;47:757-65 pubmed publisher
  • western blot; human; 1:5000; fig 3
Fu H, Martin M, Regairaz M, Huang L, You Y, Lin C, et al. The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage. Nat Commun. 2015;6:6746 pubmed publisher
  • western blot; human; 1:1000
Yu H, Chen Y, Huang C, Liu C, Chiou A, Wang Y, et al. β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration. J Cell Mol Med. 2015;19:934-47 pubmed publisher
  • western blot; human
Huber R, Lucas J, Gomez Sarosi L, Coleman I, Zhao S, Coleman R, et al. DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance. Oncotarget. 2015;6:2134-47 pubmed
  • western blot; human; 1:10; fig 4
Kang C, Lin J, Xu Z, Kumar S, Herr A. Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response. Anal Chem. 2014;86:10429-36 pubmed publisher
  • western blot; mouse; 1:4000; fig 2
Dvoriantchikova G, Ivanov D. Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways. Eur J Neurosci. 2014;40:3171-8 pubmed publisher
  • western blot; human; 1:1000
Yeo J, Lee E, Hendrickson E, Sobeck A. CtIP mediates replication fork recovery in a FANCD2-regulated manner. Hum Mol Genet. 2014;23:3695-705 pubmed publisher
  • western blot; mouse; 1:2000; fig 4
Al Sawaf O, Fragoulis A, Rosen C, Kan Y, Sönmez T, Pufe T, et al. Nrf2 protects against TWEAK-mediated skeletal muscle wasting. Sci Rep. 2014;4:3625 pubmed publisher
Duong P, Tenkorang M, Trieu J, McCuiston C, Rybalchenko N, Cunningham R. Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment. Biol Sex Differ. 2020;11:12 pubmed publisher
Cheng Y, Li S, Chuang W, Li C, Chen G, Chang C, et al. Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells. Int J Mol Sci. 2019;20: pubmed publisher
Garcia Bermudez J, Baudrier L, Bayraktar E, Shen Y, La K, Guarecuco R, et al. Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature. 2019;567:118-122 pubmed publisher
Bang B, Li M, Tsai K, Aoyagi H, Lee S, Machida K, et al. Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance. J Virol. 2019;93: pubmed publisher
Gama Sosa M, De Gasperi R, Perez Garcia G, Perez G, Searcy C, Vargas D, et al. Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain. Acta Neuropathol Commun. 2019;7:6 pubmed publisher
Bayraktar E, Baudrier L, Özerdem C, Lewis C, Chan S, Kunchok T, et al. MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo. Proc Natl Acad Sci U S A. 2019;116:303-312 pubmed publisher
Grimsey N, Narala R, Rada C, Mehta S, Stephens B, Kufareva I, et al. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Rep. 2018;24:3312-3323.e5 pubmed publisher
Tripurani S, Wang Y, Fan Y, Rahimi M, Wong L, Lee M, et al. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development. Mol Biol Cell. 2018;29:2784-2799 pubmed publisher
Horiuchi M, Kuga T, Saito Y, Nagano M, Adachi J, Tomonaga T, et al. The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1. J Biol Chem. 2018;293:15524-15537 pubmed publisher
Daniels L, Wallace R, Nicholson O, Wilson G, McDonald F, Jones P, et al. Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats. Cardiovasc Diabetol. 2018;17:89 pubmed publisher
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
Sung K, Ferrari L, Yang W, Chung C, Zhao X, Gu Y, et al. Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception. J Neurosci. 2018;38:3394-3413 pubmed publisher
Le C, Nguyen G, Park S, Choi D, Cho E. LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate-G-protein couple receptor 91 (GPR91) pathway in mice. PLoS ONE. 2018;13:e0192146 pubmed publisher
Arakaki A, Pan W, Lin H, Trejo J. The α-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling. J Biol Chem. 2018;293:3350-3362 pubmed publisher
Su W, Yu W, Huang S, Lai M. Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein Is Crucial for Production of Infectious Virus Particles. J Virol. 2018;92: pubmed publisher
Bouhy D, Juneja M, Katona I, Holmgren A, Asselbergh B, de Winter V, et al. A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8. Acta Neuropathol. 2018;135:131-148 pubmed publisher
Thompson E, Yeo J, Lee E, Kan Y, Raghunandan M, Wiek C, et al. FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. Nucleic Acids Res. 2017;45:11837-11857 pubmed publisher
Brifault C, Gilder A, Laudati E, Banki M, Gonias S. Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation. J Biol Chem. 2017;292:18699-18712 pubmed publisher
Rong X, Wang B, Palladino E, de Aguiar Vallim T, Ford D, Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest. 2017;127:3640-3651 pubmed publisher
Xiao X, Yang H, Arutiunian V, Fang Y, Besse G, Morimoto C, et al. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Res. 2017;45:7494-7506 pubmed publisher
Costigliola N, Ding L, Burckhardt C, Han S, Gutierrez E, Mota A, et al. Vimentin fibers orient traction stress. Proc Natl Acad Sci U S A. 2017;114:5195-5200 pubmed publisher
Zhang J, Johnson J, He J, Napolitano G, Ramadass M, Rocca C, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017;292:10328-10346 pubmed publisher
Fujiki K, Inamura H, Miyayama T, Matsuoka M. Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. J Biol Chem. 2017;292:7942-7953 pubmed publisher
Ainscough J, MacLeod T, McGonagle D, Brakefield R, Baron J, Alase A, et al. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?. Proc Natl Acad Sci U S A. 2017;114:E2748-E2757 pubmed publisher
Damiani E, Puebla Osorio N, Lege B, Liu J, Neelapu S, Ullrich S. Platelet activating factor-induced expression of p21 is correlated with histone acetylation. Sci Rep. 2017;7:41959 pubmed publisher
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed publisher
Bressan R, Dewari P, Kalantzaki M, Gangoso E, Matjusaitis M, Garcia Diaz C, et al. Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells. Development. 2017;144:635-648 pubmed publisher
Lin Y, Jean Y, Lee H, Lin S, Pan C, Chen W, et al. Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis. Mar Drugs. 2017;15: pubmed publisher
Schultz A, Preussner M, Bunse M, Karni R, Heyd F. Activation-Dependent TRAF3 Exon 8 Alternative Splicing Is Controlled by CELF2 and hnRNP C Binding to an Upstream Intronic Element. Mol Cell Biol. 2017;37: pubmed publisher
Zhou W, Zhou L, Shi H, Leng Y, Liu B, Zhang S, et al. Expression of glycine receptors and gephyrin in rat medial vestibular nuclei and flocculi following unilateral labyrinthectomy. Int J Mol Med. 2016;38:1481-1489 pubmed publisher
Sheets J, Iwanicki M, Liu J, Howitt B, Hirsch M, Gubbels J, et al. SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance. Oncogenesis. 2016;5:e264 pubmed publisher
Hong C, Hamilton B. Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function. PLoS Genet. 2016;12:e1006357 pubmed publisher
Zhang D, Bergsneider M, Wang M, Heaney A. Targeting the ERK pathway for the treatment of Cushing's disease. Oncotarget. 2016;7:69149-69158 pubmed publisher
Kuga T, Kume H, Adachi J, Kawasaki N, Shimizu M, Hoshino I, et al. Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON. Sci Rep. 2016;6:34472 pubmed publisher
Gan Z, Ding L, Burckhardt C, Lowery J, Zaritsky A, Sitterley K, et al. Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration. Cell Syst. 2016;3:252-263.e8 pubmed publisher
Xiao X, Li S, Yang H, Chen X. Crystal structures of APOBEC3G N-domain alone and its complex with DNA. Nat Commun. 2016;7:12193 pubmed publisher
Jiang P, Zhang P, Mukthavaram R, Nomura N, Pingle S, Teng D, et al. Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells. Oncotarget. 2016;7:57932-57942 pubmed publisher
Xu W, Weissmiller A, White J, Fang F, Wang X, Wu Y, et al. Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration. J Clin Invest. 2016;126:1815-33 pubmed publisher
Moreno Lorenzana D, Avilés Vazquez S, Sandoval Esquivel M, Alvarado Moreno A, Ortiz Navarrete V, Torres Martínez H, et al. CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI. Cell Cycle. 2016;15:1276-87 pubmed publisher
Pai C, Yen C, Chen C, Yu I, Lin S, Lin S. Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy. PLoS ONE. 2016;11:e0151617 pubmed publisher
Chou C, Wu C, Chen J, Ng M, Wang H, Chen J, et al. BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9. Int J Mol Sci. 2015;16:15104-17 pubmed publisher
Virts E, Jankowska A, MacKay C, Glaas M, Wiek C, Kelich S, et al. AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia. Hum Mol Genet. 2015;24:5093-108 pubmed publisher
Egerman M, Cadena S, Gilbert J, Meyer A, Nelson H, Swalley S, et al. GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration. Cell Metab. 2015;22:164-74 pubmed publisher
Fragkouli A, Doxakis E. miR-7 and miR-153 protect neurons against MPP(+)-induced cell death via upregulation of mTOR pathway. Front Cell Neurosci. 2014;8:182 pubmed publisher
Lin C, Shen M, Kao S, Wu D. The effect of sesamin on airway fibrosis in vitro and in vivo. Int Immunopharmacol. 2014;22:141-50 pubmed publisher
Kohsaka S, Shukla N, Ameur N, Ito T, Ng C, Wang L, et al. A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations. Nat Genet. 2014;46:595-600 pubmed publisher
James A, Shen J, Khadarian K, Pang S, Chung G, Goyal R, et al. Lentiviral delivery of PPAR? shRNA alters the balance of osteogenesis and adipogenesis, improving bone microarchitecture. Tissue Eng Part A. 2014;20:2699-710 pubmed publisher
Johnson M, Vidoni S, Durigon R, Pearce S, Rorbach J, He J, et al. Amino acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis. PLoS ONE. 2014;9:e93597 pubmed publisher
Grabiner B, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, et al. A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity. Cancer Discov. 2014;4:554-63 pubmed publisher
Colbert L, Petrova A, Fisher S, Pantazides B, Madden M, Hardy C, et al. CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer. Cancer Res. 2014;74:2677-87 pubmed publisher
Morcavallo A, Buraschi S, Xu S, Belfiore A, Schaefer L, Iozzo R, et al. Decorin differentially modulates the activity of insulin receptor isoform A ligands. Matrix Biol. 2014;35:82-90 pubmed publisher
Son J, Shen S, Margueron R, Reinberg D. Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin. Genes Dev. 2013;27:2663-77 pubmed publisher
Angulo Rojo C, Manning Cela R, Aguirre A, Ortega A, Lopez Bayghen E. Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA. ASN Neuro. 2013;5:e00130 pubmed publisher
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Cho Y, Hong C, Hou A, Gent P, Zhang K, Won K, et al. Zfp423 binds autoregulatory sites in p19 cell culture model. PLoS ONE. 2013;8:e66514 pubmed publisher
Chaudhury I, Sareen A, Raghunandan M, Sobeck A. FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery. Nucleic Acids Res. 2013;41:6444-59 pubmed publisher
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product information
Catalog No :
GTX627408
Product Name :
GAPDH antibody [GT239]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
list of Pubmed id :
24406502,24389353,24286475,24352422,24276239,22734001,23295675,23060438,23762491,23658231,24176978,23312283,24161787,23616551,24626090,24718614,24631838,24793135,24785569,24978608,25160799,25226230,25683605,25879486
Clone :
GT239
Isotype :
IgG2b
Product Description :
Mouse Monoclonal antibody [GT239] to GAPDH (glyceraldehyde-3-phosphate dehydrogenase)
CrossReactivity :
Hu, Ms, Dm, Rat, Zfsh, Yeast
Background :
The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. [provided by RefSeq]
Immunogen :
Recombinant protein encompassing a sequence within the center region of human GAPDH. The exact sequence is proprietary.
Buffer :
PBS
Uses :
ICC/IF, IHC-P, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Image Legend_4 :
GAPDH antibody [GT239] detects GAPDH protein by Western blot analysis. A. 20 µg 293T whole cell lysate/extract B. 10 µg 293T whole cell lysate/extract C. 5 µg 293T whole cell lysate/extract D. 1 µg 293T whole cell lysate/extract 10 % SDS-PAGE GAPDH antibody [GT239] (GTX627408) dilution: 1:10000
Image Legend_5 :
GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg NIH-3T3 whole cell lysate/extract C. 30 μg mouse brain lysate/extract D. 30 μg PC-12 whole cell lysate/extract E. 30 μg rat brain lysate/extract 10 % SDS-PAGE GAPDH antibody [GT239] (GTX627408) dilution: 1:10000
Image Legend_6 :
GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg Raji whole cell lysate/extract C. 30 μg 293T whole cell lysate/extract D. 30 μg A431 whole cell lysate/extract E. 30 μg HeLa whole cell lysate/extract F. 30 μg HepG2 whole cell lysate/extract G. 30 μg H1299 whole cell lysate/extract H. 30 μg HCT116 whole cell lysate/extract I. 30 μg MCF-7 whole cell lysate/extract J. 30 μg NT2D1 whole cell lysate/extract K. 30 μg PC-3 whole cell lysate/extract L. 30 μg U87-MG whole cell lysate/extract 10 % SDS-PAGE GAPDH antibody [GT239] (GTX627408) dilution: 1:10000
Image Legend_7 :
GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. A. 30 μg yeast whole cell lysate/extract 10 % SDS-PAGE GAPDH antibody [GT239] (GTX627408) dilution: 1:10000
Image Legend_8 :
Sample (30 ug of whole cell lysate) A: Drosophila 10% SDS PAGE GTX627408 diluted at 1:5000
more info or order :
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA