Filamin A antibody [EP2405Y] | GeneTex GTX61826 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Filamin A antibody [EP2405Y]

catalog :

GTX61826

quantity :

100.00μl

price :

329 USD

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

EP2405Y

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, FACS, immunohistochemistry - paraffin section

citations: 2

Reference
Marzoq A, Giese N, Hoheisel J, Alhamdani M. Proteome variations in pancreatic stellate cells upon stimulation with proinflammatory factors. J Biol Chem. 2013;288:32517-27 pubmed publisher
Steenblock C, Heckel T, Czupalla C, Espírito Santo A, Niehage C, Sztacho M, et al. The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts. J Biol Chem. 2014;289:18347-59 pubmed publisher

product information

Catalog No :

GTX61826

Product Name :

Filamin A antibody [EP2405Y]

Host Species :

Rabbit

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

List Price :

329 USD

list of Pubmed id :

24089530,24821726

Clone :

EP2405Y

Isotype :

IgG

Product Description :

Rabbit monoclonal antibody [EP2405Y] to Filamin A

CrossReactivity :

Hu, Ms, Rat

Background :

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Immunogen :

A synthetic peptide corresponding to residues near the C terminal of human Filamin A.

Buffer :

PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide.

Uses :

FACS, ICC/IF, IHC-P, WB

General References :

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Image Legend_4 :

WB analysis of lysates from (1) COS-1, (2) HeLa, (3) 3T3 and (4) C6 cells (10 μg per lane) using Filamin A antibody [EP2405Y] at a dilution of 1:500,000.