Bax antibody [E63] | GeneTex GTX61026 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Bax antibody [E63]

catalog :

GTX61026

quantity :

100.00μl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E63

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, FACS, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2c	Chou H, Fong Y, Lin H, Tsai E, Chen J, Chang W, et al. An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation. Oxid Med Cell Longev. 2016;2016:9128102 pubmed

product information

Catalog No :

GTX61026

Product Name :

Bax antibody [E63]

Host Species :

Rabbit

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

Clone :

E63

Isotype :

IgG

Product Description :

Rabbit monoclonal antibody [E63] to Bax

CrossReactivity :

Hu, Ms, Rat

Background :

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]

Immunogen :

Synthetic peptide within Human Bax aa 1-100 (N terminal). The exact sequence is proprietary.

Buffer :

PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide.

Uses :

ELISA, FACS, ICC/IF, IHC-P, IP, WB

Concentration :

0.114mg/ml

General References :

Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.