MCP1 / CCL2 antibody [2D8] | GeneTex GTX60582 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

MCP1 / CCL2 antibody [2D8]

catalog :

GTX60582

quantity :

100.00μg

price :

289 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D8

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, FACS, immunohistochemistry - paraffin section

citations: 1

Reference
McMillin M, Frampton G, Thompson M, Galindo C, Standeford H, Whittington E, et al. Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline. J Neuroinflammation. 2014;11:121 pubmed publisher

product information

Catalog No :

GTX60582

Product Name :

MCP1 / CCL2 antibody [2D8]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

289 USD

list of Pubmed id :

25012628

Clone :

2D8

Isotype :

IgG1

Product Description :

Mouse Monoclonal Antibody [2D8] to CCL2

CrossReactivity :

Hu, Ms, Mk

Background :

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]

Immunogen :

The immunogen corresponding to human CCL2 expressed in E. Coli.

Buffer :

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.

Uses :

ELISA, FACS, ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

4°C; -20°C for long term storage

Image Legend_4 :

Immunofluorescence analysis of HepG2 cells using CCL2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Image Legend_5 :

Flow cytometric analysis of A549 cells using CCL2 mouse mAb (green) and negative control (red).