This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
JNK1/2/3 (phospho Thr183/Thr185) antibody
catalog :
GTX59583
quantity :
50.00μg
price :
269 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunoprecipitation
product information
Catalog No :
GTX59583
Product Name :
JNK1/2/3 (phospho Thr183/Thr185) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen Modification :
Phosphorylated
Product Type :
Primary antibody
Size :
50.00μg
List Price :
269 USD
Isotype :
IgG
Product Description :
Rabbit Polyclonal antibody to JNK1
CrossReactivity :
Hu, Ms, Rat
Background :
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
Specificity :
This antibody is specific for JNK/SAPK (phospho Thr183/Tyr185).
Buffer :
PBS (pH 7.2) containing 50% glycerol, 1% BSA, 0.02% sodium azide
Uses :
IHC, IP
Concentration :
0.5mg/ml
General References :
The antibody solution should be gently mixed before use. Store at -20C. Product should remain stable for at least 12 months.
company information
GeneTex
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