Mek1/2 (phospho Ser217/Ser221) antibody | GeneTex GTX59582 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Mek1/2 (phospho Ser217/Ser221) antibody

catalog :

GTX59582

quantity :

50.00μl

price :

269 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 2

Reference
Sinanoğlu O, Yener A, Ekici S, Midi A, Aksungar F. The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. Urology. 2012;80:1392.e1-6 pubmed publisher
Tseng H, Li C, Huang L, Chen C, Tsai C, Lin C, et al. Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway. Toxicol Appl Pharmacol. 2012;264:104-13 pubmed publisher

product information

Catalog No :

GTX59582

Product Name :

Mek1/2 (phospho Ser217/Ser221) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μl

List Price :

269 USD

list of Pubmed id :

22951000,22842013

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to Mek1/2 (phospho Ser217/Ser221)

CrossReactivity :

Hu, Ms, Rat

Background :

MAP kinase kinase 1 (Mek1), also known as mitogen activated protein kinase kinase, MAP kinase kinase, ERK kinase 1 or microtubule-associated protein 2 kinase, is a 43 kDa dual-specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine-threonine kinase, Raf-1, which is part of the p21ras signal transduction pathway.

Specificity :

This antibody is specific for Mek1/2 (phospho Ser217/Ser221).

Buffer :

PBS (pH 7.2) containing 50% glycerol, 1% BSA, and 0.02% sodium azide

Uses :

ICC/IF, WB

Concentration :

0.5mg/ml

General References :

The antibody solution should be gently mixed before use. Store at +4C. Product should remain stable for at least 12 months.