This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Tau antibody [B11E8]
catalog :
GTX59570
quantity :
50.00μl
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B11E8
reactivity :
human
application :
immunohistochemistry, immunoprecipitation
product information
Catalog No :
GTX59570
Product Name :
Tau antibody [B11E8]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
50.00μl
List Price :
269 USD
Clone :
B11E8
Isotype :
IgG1
Product Description :
Mouse monoclonal antibody [B11E8 ] to Tau
CrossReactivity :
Hu
Background :
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer’s disease. Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer’s disease.
Specificity :
This antibody is specific for Tau-13.
Buffer :
PBS (pH 7.2) containing 50% glycerol, 1% BSA, and 0.02% sodium azide
Uses :
IHC, IP
General References :
The antibody solution should be gently mixed before use. Store at +4C. Product should remain stable for at least 12 months.
company information
GeneTex
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