VEGF antibody | GeneTex GTX54662 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

VEGF antibody

catalog :

GTX54662

quantity :

30.00μg

price :

369 USD

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

product information

Catalog No :

GTX54662

Product Name :

VEGF antibody

Host Species :

Chicken

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

30.00μg

List Price :

369 USD

Isotype :

IgY

Product Description :

Chicken Polyclonal antibody to VEGF

CrossReactivity :

Background :

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]

Immunogen :

The partially reduced homodimmers and multimers that VEGF spontaneously forms.

Uses :

ICC/IF, WB

General References :

Lyophilized antibody can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20ºC) or for long-term storage (-80ºC).