VEGF 165 + VEGF 121 antibody [2B86] | GeneTex GTX52462 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

VEGF 165 + VEGF 121 antibody [2B86]

catalog :

GTX52462

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B86

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

product information

Catalog No :

GTX52462

Product Name :

VEGF 165 + VEGF 121 antibody [2B86]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

Clone :

2B86

Isotype :

IgG2

Product Description :

Mouse monoclonal antibody [2B86] to VEGF 165 + VEGF 121

CrossReactivity :

Background :

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]

Immunogen :

human VEGF-A 165 recombinant protein

Specificity :

This antibody detects both human VEGF 165 and 121.

Buffer :

PBS

Uses :

IHC-P, WB

General References :

Reconstituted antibody can also be aliquoted and stored frozen at -20 for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.