I kappa B alpha (phospho Ser32/Ser36) antibody | GeneTex GTX50209 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

I kappa B alpha (phospho Ser32/Ser36) antibody

catalog :

GTX50209

quantity :

100.00μl

price :

299 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Catalog No :

GTX50209

Product Name :

I kappa B alpha (phospho Ser32/Ser36) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

100.00μl

List Price :

299 USD

Product Description :

Rabbit Polyclonal antibody to I kappa B alpha (Phospho Ser32/Ser36)

CrossReactivity :

Hu, Ms, Rat

Background :

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

Immunogen :

Peptide sequence around phosphorylation site of serine 32/36 (H-D-S(p)-G-L-D-S(p)-M-K) derived from Human I kappa B alpha .

Buffer :

saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Uses :

ICC/IF, IHC, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.