NeuN antibody [2Q158] | GeneTex GTX30773 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

NeuN antibody [2Q158]

catalog :

GTX30773

quantity :

250.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

GeneTex product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; fig 1	Telias M, Mayshar Y, Amit A, Ben-Yosef D. Molecular mechanisms regulating impaired neurogenesis of fragile X syndrome human embryonic stem cells. Stem Cells Dev. 2015;24:2353-65 pubmed publisher
	Jeong J, Yu K, Bak D, Lee J, Lee N, Jeong Y, et al. Intermittent fasting is neuroprotective in focal cerebral ischemia by minimizing autophagic flux disturbance and inhibiting apoptosis. Exp Ther Med. 2016;12:3021-3028 pubmed
	Telias M, Segal M, Ben-Yosef D. Electrical maturation of neurons derived from human embryonic stem cells. F1000Res. 2014;3:196 pubmed publisher
	Ylä-Outinen L, Joki T, Varjola M, Skottman H, Narkilahti S. Three-dimensional growth matrix for human embryonic stem cell-derived neuronal cells. J Tissue Eng Regen Med. 2014;8:186-94 pubmed publisher
	Di-Poï N, Milinkovitch M. Crocodylians evolved scattered multi-sensory micro-organs. Evodevo. 2013;4:19 pubmed publisher
	Liang L, Fan L, Tao B, Yaster M, Tao Y. Protein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons. J Pain. 2013;14:638-47 pubmed publisher

image

image 1 :

Neuron Specific Nuclear Protein (NeuN) antibody [2Q158] detects NeuN protein on rat cerebellumn by IHC-P analysis.(Citrate Buffer, pH 6.0.) Dilution:1:100 Immunoreactivity is seen as nuclear staining in the neurons in the granular layer.

image 2 :

Neuron Specific Nuclear Protein (NeuN) antibody [2Q158] detects NeuN protein on mouse brain(dentate gyrus and subventricular zone) by IHC-P analysis.(Citrate Buffer, pH 6.0.)

product information

Catalog No :

GTX30773

Product Name :

NeuN antibody [2Q158]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

250.00μg

List Price :

299 USD

list of Pubmed id :

23642408,23819918,22611014

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody to NeuN

CrossReactivity :

Hu, Ms, Rat, Frt, Slm

Background :

Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN (Neuronal Nuclei) is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus, and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia, and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain, as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

Immunogen :

Purified cell nuclei from mouse brain

Specificity :

Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei). Recognizes 2-3 bands in the 46-48kD range and possibly another band at approximately 66kD

Buffer :

PBS, pH 7.4 containing 0.1% sodium azide and 40% glycerol

Uses :

ICC/IF, IHC-Fr, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

more info or order :

GeneTex product webpage