DNMT1 antibody | GeneTex GTX30364 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

DNMT1 antibody

catalog :

GTX30364

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Catalog No :

GTX30364

Product Name :

DNMT1 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

12496760,12015329

Product Description :

Anti - DNMT1 polyclonal

CrossReactivity :

Background :

Inactivation of tumor suppressor genes is a key component of the development of all common forms of human cancers. Aberrant methylation may contribute to many of the changes, both physiological and pathological, associated with aging, including tumor development. Hypermethylation of CpG island-containing promoters is associated with the inactivation of genes important to tumor angiogenesis and progression. DNA methytransferase (DNMT1) is necessary for the maintenance of the methylation process.

Immunogen :

This antibody was raised against the first 10 kDa of the N-terminus of the DNMT1 protein.

Specificity :

This antibody is specific for DNMT1.

Uses :

ICC/IF, IHC-P, IP, WB

General References :

Keep as concentrated solution, aliquot and store at 4°C.

Image Legend_4 :

Western Blot: Dnmt1 Antibody [GTX30364] - Analysis using GTX30364 to detect DNMT1 levels in T24 degrees Cells. Lane 1: 50 ugs of total protein lysate from untreated T24 degrees Cells. Lane 2: 50 ugs of total protein lysate treated with 0.5 uM 5-Aza-Deoxycytidine for 3 days.