NBS1 antibody | GeneTex GTX30125 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

NBS1 antibody

catalog :

GTX30125

quantity :

50.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog No :

GTX30125

Product Name :

NBS1 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

50.00μl

list of Pubmed id :

12799193,11916980,11282395

Product Description :

Rabbit polyclonal to p95 / nibrin / NBS1

CrossReactivity :

Background :

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Immunogen :

NBS1 (aa 1-705)

Specificity :

This antibody is specific for hp95.

Buffer :

50 µl of antisera containing 0.02% sodium azide.

Uses :

ICC/IF, IP, WB

Concentration :

antiserum

General References :

Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.

Image Legend_4 :

Western Blot: NBS1 Antibody (GTX30125) - Detection of NBS1 in Human Bone Osteosarcoma Epithelial Cells (U2OS whole cell lysate) using GTX30125 at a dilution of 1/1000. Specificity was confirmed using a siRNA anti-NBS1 (targeting sequence: GGAAGAAACGUGAACUCAA).