This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD21 antibody [1F8]
catalog :
GTX29492
quantity :
250.00μl
price :
259 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1F8
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog No :
GTX29492
Product Name :
CD21 antibody [1F8]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
250.00μl
List Price :
259 USD
Clone :
1F8
Isotype :
IgG1
Product Description :
Mouse monoclonal [1F8] to CD21
CrossReactivity :
Hu
Background :
CD21 also known as complement receptor 2 (CR2). C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23-signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
Immunogen :
Purified receptor for the C3d fragment of the third complement component CR2.
Specificity :
This antibody reacts with CD21 antigen of MW 145 kDa, present on the surface of mature B cells. The antigen is present at high density on follicular dendritic cells. CD21 is involved in transmitting growth promoting signals to the interior of the B cell.
Buffer :
This antibody contains sodium azide as a preservative.
Uses :
IHC, IHC-Fr, IHC-P
Concentration :
batch dependent
General References :
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
company information
GeneTex
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