Estrogen Receptor alpha antibody [6F11] | GeneTex GTX29269 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Estrogen Receptor alpha antibody [6F11]

catalog :

GTX29269

quantity :

250.00μl

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6F11

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Reference
Belcher S, Ma X, Le H. Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma. Endocrinology. 2009;150:1112-21 pubmed publisher

product information

Catalog No :

GTX29269

Product Name :

Estrogen Receptor alpha antibody [6F11]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

250.00μl

List Price :

369 USD

list of Pubmed id :

19008315

Clone :

6F11

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [6F11] to Estrogen Receptor alpha

CrossReactivity :

Background :

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]

Immunogen :

Recombinant human estrogen receptor (alpha form)

Specificity :

This antibody recognizes human estrogen receptor alpha chain.

Uses :

IHC-Fr, IHC-P, WB

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.