TLR4 antibody [HTA125] (FITC) | GeneTex GTX28378 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

TLR4 antibody [HTA125] (FITC)

catalog :

GTX28378

quantity :

50.00μg

price :

289 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

HTA125

reactivity :

human, dog

application :

immunocytochemistry, FACS

citations: 1

Reference
Krupa A, Fudala R, Florence J, Tucker T, Allen T, Standiford T, et al. Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils. Am J Respir Cell Mol Biol. 2013;48:240-9 pubmed publisher

product information

Catalog No :

GTX28378

Product Name :

TLR4 antibody [HTA125] (FITC)

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

FITC

Product Type :

Primary antibody

Size :

50.00μg

List Price :

289 USD

list of Pubmed id :

23239500

Clone :

HTA125

Isotype :

IgG2a

Product Description :

Mouse monoclonal antibody [HTA125] to TLR4

CrossReactivity :

Hu, Dog, Pig, Gpig, RMK

Background :

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Specificity :

This antibody recognizes the human Toll like receptor 4 (TLR4).

Buffer :

Phosphate buffered saline containing 0.09% Sodium Azide 1% Bovine Serum Albumin

Uses :

FACS, ICC/IF

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Image Legend_4 :

Staining of U937 cells with Mouse anti Human CD284:RPE (GTX11227)