beta III Tubulin antibody [TU-20] | GeneTex GTX27751 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

beta III Tubulin antibody [TU-20]

catalog :

GTX27751

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TU-20

reactivity :

human, mouse, rat, cow

application :

immunohistochemistry, immunocytochemistry, FACS

citations: 3

Reference
Lehmann M, Nguemo F, Wagh V, Pfannkuche K, Hescheler J, Reppel M. Evidence for a critical role of catecholamines for cardiomyocyte lineage commitment in murine embryonic stem cells. PLoS ONE. 2013;8:e70913 pubmed publisher
Chien H, Wang H, Su Y, Lai K, Lu L, Chen P, et al. Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage. PLoS ONE. 2012;7:e47481 pubmed publisher
Park J, Kim M, Kim C, Kim J. Intracranial extraskeletal myxoid chondrosarcoma : case report and literature review. J Korean Neurosurg Soc. 2012;52:246-9 pubmed

product information

Catalog No :

GTX27751

Product Name :

beta III Tubulin antibody [TU-20]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

23115670,23071813

Clone :

TU-20

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [TU-20] to beta III Tubulin

CrossReactivity :

Hu, Ms, Cow, Pig, Rat, Bb, Carp, Hm, Mamm

Background :

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq]

Immunogen :

Synthetic peptide: ESESQGPK conjugated to malemide activated KLH, corresponding to amino acids 441-448 of Human Tubulin.

Specificity :

Class III beta-tubulin specific for neurones.

Buffer :

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Uses :

FACS, ICC/IF, IHC

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

Image Legend_4 :

Immunofluorescence staining of P-19 mouse embryonal carcinoma cell line stimulated to neuronal differentiation by retinoic acid. 2B - Merged image of co-staining with anti-beta-tubulin (GTX27792). Superposition of red and green colours provided yellow staining. Nuclei were stained with DNA-binding dye (blue).

Image Legend_5 :

Immunofluorescence staining of P-19 mouse embryonal carcinoma cell line stimulated to neuronal differentiation by retinoic acid. 2A - Microtubules decorated with neuron-specific anti-betaIII-tubulin (GTX27751; red).