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product summary
company name :
GeneTex
product type :
antibody
product name :
Insulin antibody [K36AC10]
catalog :
GTX26995
quantity :
50.00μl
price :
259 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K36aC10
reactivity :
human, rat, dog
application :
radioimmunoassay, immunohistochemistry - paraffin section
product information
Catalog No :
GTX26995
Product Name :
Insulin antibody [K36AC10]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
50.00μl
List Price :
259 USD
Clone :
K36AC10
Isotype :
IgG1
Product Description :
Mouse monoclonal to Insulin
CrossReactivity :
Hu, Cow, Dog, Pig, Rat, Cat, Gpig, Hrs, Rb, Shp
Background :
Monoclonal Anti-Insulin may be used for the localization of insulin using RIA, dot blot and immunocytochemistry. Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma. Insulin-specific antibodies prove useful as b-cell and tumor markers using immunohistochemical techniques, and as analytical tools in quantification of the hormone.
Specificity :
The antibody exhibits cross-reactivity with human proinsulin (ref 3).
Buffer :
15 mM Na azide
Uses :
Dot, IHC-P, RIA
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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