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product summary
company name :
GeneTex
product type :
antibody
product name :
Collagen I antibody (Biotin)
catalog :
GTX26577
quantity :
50.00μg
price :
289 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human, cow
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog No :
GTX26577
Product Name :
Collagen I antibody (Biotin)
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Biotin
Product Type :
Primary antibody
Size :
50.00μg
List Price :
289 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to Collagen I (Biotin)
CrossReactivity :
Hu, Cow, Mamm
Background :
This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix, which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
Immunogen :
Collagen Type I from adult human and bovine tissues.
Specificity :
Negligible cross-reactivity with Type II, III, IV, V or VI collagens. Non-specific cross reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible.
Buffer :
0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005M EDTA, pH 8.0, 10 mg/ml Bovine Serum Albumin, and 0.01% (w/v) Sodium Azide
Uses :
ELISA, IHC-Fr, IHC-P, IM, IP, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage add 50% glycerol, aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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