Collagen IV antibody [COL-94] | GeneTex GTX26311 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Collagen IV antibody [COL-94]

catalog :

GTX26311

quantity :

100.00μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

COL-94

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; loading ...; fig 1d	McLane J, Ligon L. Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model. Cancer Microenviron. 2016;9:127-139 pubmed publisher

product information

Catalog No :

GTX26311

Product Name :

Collagen IV antibody [COL-94]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

Clone :

COL-94

Isotype :

IgG1

Product Description :

Mouse monoclonal [COL - 94] to Collagen IV

CrossReactivity :

Hu, NHuPrm

Background :

Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.

Immunogen :

Full length native protein (purified) (Human).

Specificity :

Specifically recognizes native, undenatured, human collagen type IV . Shows no cross reactivity with collagen types I, II, III, V, VI, VII, human vitronectin, fibronectin, or chondroitin sulfate A. B and C. No reactivity with denatured or denatured-reduced collagen in immunoblots.

Buffer :

Preservative: 15mM Sodium Azide; Constituents: Ascites fluid

Uses :

Dot, ELISA, IA, ICC/IF, IHC-F, IHC-P, WB

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.