Collagen I antibody [COL-1] | GeneTex GTX26308 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Collagen I antibody [COL-1]

catalog :

GTX26308

quantity :

100.00μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

COL-1

reactivity :

human, rat, bovine, pigs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; pigs ; 1:1000; fig 3	Wu Q, Bao J, Zhou Y, Wang Y, Du Z, Shi Y, et al. Optimizing perfusion-decellularization methods of porcine livers for clinical-scale whole-organ bioengineering. Biomed Res Int. 2015;2015:785474 pubmed publisher
	Bao J, Wu Q, Wang Y, Li Y, Li L, Chen F, et al. Enhanced hepatic differentiation of rat bone marrow-derived mesenchymal stem cells in spheroidal aggregate culture on a decellularized liver scaffold. Int J Mol Med. 2016;38:457-65 pubmed publisher
	Delella F, Lacorte L, Almeida F, Pai M, Felisbino S. Fibrosis-related gene expression in the prostate is modulated by doxazosin treatment. Life Sci. 2012;91:1281-7 pubmed publisher

product information

Catalog No :

GTX26308

Product Name :

Collagen I antibody [COL-1]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

23069578,25918720

Clone :

COL-1

Isotype :

IgG1

Product Description :

Mouse monoclonal [COL - 1] to Collagen I

CrossReactivity :

Hu, Pig, Rat, Deer, Rb

Background :

Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

Immunogen :

Full length native protein (purified) (Cow).

Specificity :

Recognises the native (helical) form of collagen type I using ELISA and dot-blot. Does not react with the thermally-denatured molecule. The antibody shows no cross-reactivity with collagen types II, III, IV, V, VI, VII, IX, X and XI.

Buffer :

Phosphate-buffered saline, pH 7.2 with 15 mM sodium azide.

Uses :

Dot, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB

Concentration :

Ascites

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.