CaMKII alpha (phospho Thr286) antibody | GeneTex GTX25683 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

CaMKII alpha (phospho Thr286) antibody

catalog :

GTX25683

quantity :

50.00μl

price :

289 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot

product information

Catalog No :

GTX25683

Product Name :

CaMKII alpha (phospho Thr286) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μl

List Price :

289 USD

Isotype :

IgG

Product Description :

Rabbit polyclonal to CaMKII alpha ( phospho T286 )

CrossReactivity :

Ms, Rat

Background :

Calcium/calmodulin-dependent protein kinase II alpha (CaM Kinase II alpha) is a 50 kDa member of CaM Kinase II family of serine-threonine kinases that transduce Ca2+ signals to several target proteins, including ion channels and transcription activators. CaM Kinase II is predominantly expressed in two isoforms in the brain: alpha and beta. CaM Kinase II plays an important role in neuronal plasticity and memory formation, and exerts both calcium-calmodulin-dependent and -independent activities. Autophosphorylation of CaM Kinase II alpha on threonine 286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state, and is required for various cellular functions including hippocampal long-term potentiation (LTP), special learning, and hippocampus-dependent memory.

Immunogen :

Synthetic phosphopeptide derived from a region of human CaM Kinase II alpha that contains threonine 286.

Buffer :

Preservative: 0.05% Sodium Azide; Constituents: 50% Glycerol, PBS, 1mg/ml BSA. pH 7.3

Uses :

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.