VEGFR-2 (phospho Tyr1054) antibody | GeneTex GTX25472 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

VEGFR-2 (phospho Tyr1054) antibody

catalog :

GTX25472

quantity :

50.00μl

price :

289 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot

product information

Catalog No :

GTX25472

Product Name :

VEGFR-2 (phospho Tyr1054) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μl

List Price :

289 USD

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to VEGFR-2 ( phospho Y1054 )

CrossReactivity :

Hu, Ms, Rat

Background :

Vascular endothelial growth factor receptor 2 (VEGFR 2, also known as KDR / FLK 1) is a 200 kDa member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGFR 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2- and phosphotyrosine binding containing signaling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGFR 2 and its intrinsic tyrosine kinase activity.

Immunogen :

Synthetic phospho peptide containing Tyrosine 1054. The sequence is conserved in mouse and rat.

Specificity :

VEGFR 3 (100%) has not been tested, but is expected to react.

Buffer :

Preservative: 0.05% Sodium Azide; Constituents: PBS, 1mg/ml BSA (IgG, protease free). pH 7.3

Uses :

Concentration :

0.5mg/ml

General References :

Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.