PDGFR alpha (phospho Tyr754) antibody | GeneTex GTX25460 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

PDGFR alpha (phospho Tyr754) antibody

catalog :

GTX25460

quantity :

50.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Catalog No :

GTX25460

Product Name :

PDGFR alpha (phospho Tyr754) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μl

list of Pubmed id :

25686615

Isotype :

IgG

Product Description :

Rabbit polyclonal to PDGF Receptor alpha ( phospho Y754 )

CrossReactivity :

Hu, Ms, Rat, Xl

Background :

Platelet-derived growth factor receptor (PDGFR) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo- or heterodimerization upon ligand binding. The phosphorylation of tyrosine residues in the activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation, and also lead to activation of the Ras, Raf and ERK 1 and 2 pathway. Phosphorylation of tyrosine 754 is thought to initiate specific signal-transduction pathways distinct from those initiated via homodimeric receptor complexes, as tyrosine 754 has not been shown to be phosphorylated in those complexes.

Immunogen :

Synthetic phospho peptide (Human) containing Tyrosine 754.

Specificity :

PDGFR beta (50%) has not been tested, but is not expected to react.

Buffer :

Preservative: 0.05% Sodium Azide; Constituents: PBS, 1mg/ml BSA (IgG, protease free). pH 7.3

Uses :

ICC/IF, WB

Concentration :

0.5mg/ml