This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Lamin B antibody [X223]
catalog :
GTX24825
quantity :
1.00 ml
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
X223
reactivity :
human, mouse, rat, cow
application :
western blot, immunocytochemistry
product information
Catalog No :
GTX24825
Product Name :
Lamin B antibody [X223]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
1.00 ml
List Price :
289 USD
Clone :
X223
Isotype :
IgG1
Product Description :
Mouse Monoclonal antibody [X223] to Lamin B
CrossReactivity :
Hu, Ms, Cow, Rat
Background :
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq]
Immunogen :
Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells)
Specificity :
This antibody decorates the karyoskeleton, i.e. the intermediate filament equivalent of the nucleus. Reacts with lamin isotypes of Mr 60 -75 kD. Recognises lamin B1 & B2 in human, bovine & rat, and lamin B2 in mouse
Buffer :
Tissue culture supernatant containing 0.09% sodium azide
Uses :
ICC/IF, WB
General References :
Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.
company information
GeneTex
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