FAK (phospho Tyr397) antibody | GeneTex GTX24803 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

FAK (phospho Tyr397) antibody

catalog :

GTX24803

quantity :

50.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunohistochemistry - frozen section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 5	Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher

product information

Catalog No :

GTX24803

Product Name :

FAK (phospho Tyr397) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μl

list of Pubmed id :

23320038

Isotype :

IgG

Product Description :

Rabbit polyclonal to FAK (phospho Y397)

CrossReactivity :

Hu, Ms, Xl

Background :

Focal Adhesion Kinase is a 125 kDa non-receptor protein tyrosine kinase that was discovered as a substrate for Src, and is a key element of integrin signaling. Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. Tyrosine 397 is the autophosphorylation site of Focal Adhesion Kinase. The site binds Src family SH2 domains and the p85 subunit of PI3-Kinase.

Immunogen :

Synthetic peptide derived from the region of Focal Adhesion Kinase that contains tyrosine 397. The sequence is conserved in human, mouse, rat, chicken and frog.

Buffer :

PBS, 1mg/ml BSA (IgG, protease free). pH 7.3 and 50% Glycerol containing 0.05% sodium azide

Uses :

ICC/IF, IHC-Fr, WB

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.