ABCG2 antibody [BXP-21] | GeneTex GTX23380 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

ABCG2 antibody [BXP-21]

catalog :

GTX23380

quantity :

250.00μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BXP-21

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Kim D, Bynoe M. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest. 2016;126:1717-33 pubmed publisher
	Yamasaki T, Fujinaga M, Kawamura K, Hatori A, Yui J, Nengaki N, et al. Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography. Nucl Med Biol. 2011;38:707-14 pubmed publisher
	Yonemori K, Tsuta K, Ono M, Shimizu C, Hirakawa A, Hasegawa T, et al. Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer. Cancer. 2010;116:302-8 pubmed publisher

product information

Catalog No :

GTX23380

Product Name :

ABCG2 antibody [BXP-21]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

250.00μl

list of Pubmed id :

19937674,21718946

Clone :

BXP-21

Isotype :

IgG2a

Product Description :

Mouse Monoclonal antibody [BXP-21] to ABCG2

CrossReactivity :

Background :

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

Immunogen :

Fusion protein composed of E. Coli maltose binding protein and BCRP peptide [126 amino acids, 271-396 AA of BCRP, GeneBank accession #AF098951].

Specificity :

This antibody does not react with the human MDR 1, MRP 1 and MRP 2 gene products.

Buffer :

Preservative: 0.1% Sodium Azide; Constituents: 1% BSA

Uses :

ICC/IF, IHC-Fr, IHC-P, WB

General References :

Keep as concentrated solution, aliquot and store at 4°C.