This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
NOTCH1 antibody [A6]
catalog :
GTX23294
quantity :
500.00μl
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A6
reactivity :
human, mouse
application :
immunohistochemistry - paraffin section
product information
Catalog No :
GTX23294
Product Name :
NOTCH1 antibody [A6]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
500.00μl
List Price :
289 USD
Clone :
A6
Isotype :
IgG2b
Product Description :
Mouse monoclonal [A6] to Notch1
CrossReactivity :
Hu, Ms
Background :
The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine rich EGF like repeats in the extracellular region. Four notch genes have been described in mammals, which include notch 1. notch 2, notch 3, and notch 4(Int 3), which have been implicated in the differentiation of the nervous system and other structures. The EGF like proteins Delta and Serrate have been identified as ligands of notch 1. Mature notch proteins are heterodimeric receptors derived from the cleavage of notch preproteins into an extracellular subunit (NEC) containing multiple EGF like repeats and a transmembrane subunit including intracellular region (Ntm). Alteration of notch 1 signaling or expression may contribute to tumorigenesis.
Immunogen :
Recombinant protein encoding the ligand binding region of human Notch 1
Specificity :
This antibody has not been tested for its cross reactivity with Notch 2.
Buffer :
Phosphate-buffered saline, pH7.4, containing 0.2% BSA and 0.1% sodium azide
Uses :
FACS, IHC-P
Concentration :
0.2mg/ml
General References :
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
company information
GeneTex
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