Hsp70 antibody [W27] | GeneTex GTX23148 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

Hsp70 antibody [W27]

catalog :

GTX23148

quantity :

500.00μl

price :

289 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

W27

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, FACS, immunohistochemistry - paraffin section

more info or order :

GeneTex product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Kaiser M, Kühnl A, Reins J, Fischer S, Ortiz Tánchez J, Schlee C, et al. Antileukemic activity of the HSP70 inhibitor pifithrin-? in acute leukemia. Blood Cancer J. 2011;1:e28 pubmed publisher
flow cytometry; human; fig 3	Lamottke B, Kaiser M, Mieth M, Heider U, Gao Z, Nikolova Z, et al. The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases. Eur J Haematol. 2012;88:406-15 pubmed publisher

product information

Catalog No :

GTX23148

Product Name :

Hsp70 antibody [W27]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

500.00μl

List Price :

289 USD

list of Pubmed id :

22309072,22829184

Clone :

W27

Isotype :

IgG2a

Product Description :

Mouse monoclonal [W27] to Hsp70

CrossReactivity :

Hu, Cow, Mk

Background :

Heat shock proteins (HSPs) or stress response proteins (SRPs) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSP's are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.

Immunogen :

HSP70 protein from HeLa cells.

Specificity :

Recognizes both the constitutive (HSP73), and inducible (HSP72) forms of HSP70.

Buffer :

Phosphate-buffered saline, pH 7.2, containing 0.2%BSA, 0.09% sodium azide

Uses :

FACS, ICC/IF, IHC-P, IP, WB

Concentration :

0.2mg/ml

General References :

Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.

more info or order :

GeneTex product webpage