Importin beta-1 antibody [3E9] | GeneTex GTX22811 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Importin beta-1 antibody [3E9]

catalog :

GTX22811

quantity :

100.00μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E9

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, FACS

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human	Yang C, Chiang C, Chen C, Lee Y, Wu M, Tsou Y, et al. Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci. 2015;22:33 pubmed publisher

product information

Catalog No :

GTX22811

Product Name :

Importin beta-1 antibody [3E9]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

Clone :

3E9

Isotype :

IgG2a

Product Description :

Mouse Monoclonal antibody to Importin beta-1

CrossReactivity :

Hu, Ms, Dog, Pig, Rat, Bov

Background :

The accumulation of proteins in the nucleus is mediated by short sequences of basic amino acids called nuclear localization sequences (NLSs). These sequences are necessary and sufficient to direct a protein or inert carrier to the nuclear interior. Nuclear protein import is accomplished by two sequential, energy dependent events. The first step, docking at the nuclear pore complex, requires a 54/56 kDa nuclear localization signal receptor (a-karyopherin, importin-a, SRP-a) and the nuclear transport factor p97 (NTF97, b-karyopherin, importin-b). The second step, translocation across the nuclear envelope (NE), requires the GTP-binding protein, Ran/TC4.

Immunogen :

Purified NTF97 from bovine erythrocytes.

Buffer :

PBS containing 1 mg/ml BSA and 0.05% sodium azide.

Uses :

Blocking, FACS, ICC/IF, IHC, Inhib, IP, WB, ChIP assay

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.