This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD40L antibody
catalog :
GTX22391
quantity :
50.00μg
price :
289 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA
product information
Catalog No :
GTX22391
Product Name :
CD40L antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
50.00μg
List Price :
289 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to CD40L
CrossReactivity :
Hu, Ms, Rat
Background :
CD40 ligand (CD40L), also known as CD154, gp39 and TRAP, is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X-linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes. CD40, also known as bp50 or CDW40, is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with T cells expressing CD40L, and activation of CD4+ T cells. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes.
Immunogen :
Highly purified recombinant human CD40L (CD40 Ligand)
Buffer :
PBS with 1 mg/ml BSA, 1.5 mM sodium azide and 50% glycerol
Uses :
ELISA, WB
Concentration :
0.5mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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