Caspase 3 (active) antibody | GeneTex GTX22302 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Caspase 3 (active) antibody

catalog :

GTX22302

quantity :

50.00μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Catalog No :

GTX22302

Product Name :

Caspase 3 (active) antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

50.00μg

list of Pubmed id :

21478186,20506465,22842013,22951000,23953563,23769908,26052286

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to Caspase 3 (active)

CrossReactivity :

Hu, Ms, Rat, Frt

Background :

Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase 3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase 3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). This affinity-purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.

Immunogen :

Available on request

Specificity :

The antibody preferentially recognizes the p17 fragment of the active Caspase 3 .

Buffer :

PBS, pH 7.4 containing 50% glycerol, 1 mg/ml BSA and 0.02% thimerosal

Uses :

ICC/IF, IHC, IHC-Fr, IHC-P, WB

Concentration :

0.2mg/ml

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.