This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
p14ARF antibody
catalog :
GTX20470
quantity :
100.00μl
price :
339 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog No :
GTX20470
Product Name :
p14ARF antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
339 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to p14ARF
CrossReactivity :
Hu, Ms
Background :
The INK4a-ARF locus is comprised of two tumor suppressors, p16INK4a and p14ARF. These two proteins are encoded through differential splicing of alternative first exons. The p16INK4a (exon 1alpha) protein inhibits the cyclin D-dependent kinases (CDK) that control the phosphorylation of the Rb protein and cell proliferation. The p14ARF gene product complexes with the MDM2 protein within the nucleus, thus modulating the activity of the p53 protein. P14ARF is a potent tumor suppressor in the presence of wild-type p53, while mutant p53 substantially reduces growth inhibition by p14ARF.
Immunogen :
A synthetic peptide made to a portion of human p14ARF (between residues 50-150) .
Specificity :
Specific for p14ARF.
Buffer :
Tris-glycine, 150mM NaCl, and 0.05% sodium azide.
Uses :
ELISA, FACS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Image Legend_4 :
Immunocytochemistry/Immunofluorescence: p14ARF Antibody (GTX20470) - p14ARF antibody was tested in HeLa cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue). Tubulin was stained with alpha tubulin (red)
company information
GeneTex
questions and comments