EGFR antibody [ICR10] | GeneTex GTX20231 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

EGFR antibody [ICR10]

catalog :

GTX20231

quantity :

100.00μg

price :

289 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

ICR10

reactivity :

human

application :

immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Catalog No :

GTX20231

Product Name :

EGFR antibody [ICR10]

Host Species :

Rat

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

289 USD

Clone :

ICR10

Isotype :

IgG2a

Product Description :

Rat monoclonal antibody [ICR10] to EGFR

CrossReactivity :

Background :

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Immunogen :

Extracellular domain of human EGF-receptor from head and neck carcinoma

Specificity :

This antibody recognizes the human epidermal growth factor receptor (EGF-R). Clone ICR10 binds to epitope B from EGFR (Lottaz et al. 2010 and Modjtahedi et al. 1993) and has an affinity of 6.7 x 10-9 M.

Buffer :

Phosphate buffered saline containing 0.09% Sodium Azide

Uses :

FACS, IHC-Fr, IHC-P, IP

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.