c-Myc antibody [9E10] | GeneTex GTX20032 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

c-Myc antibody [9E10]

catalog :

GTX20032

quantity :

200.00μg

price :

239 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9E10

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 7

Reference
Ding X, Goldberg M. Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP. PLoS ONE. 2009;4:e5949 pubmed publisher
Mabry R, Gilbertson D, Frank A, Vu T, Ardourel D, Ostrander C, et al. A dual-targeting PDGFRbeta/VEGF-A molecule assembled from stable antibody fragments demonstrates anti-angiogenic activity in vitro and in vivo. MAbs. 2010;2:20-34 pubmed
Biswas M, Kwong E, Park E, Nagra P, Chan J. Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1. Exp Cell Res. 2013;319:1922-31 pubmed publisher
Cagnac O, Leterrier M, Yeager M, Blumwald E. Identification and characterization of Vnx1p, a novel type of vacuolar monovalent cation/H+ antiporter of Saccharomyces cerevisiae. J Biol Chem. 2007;282:24284-93 pubmed
Ma M, Baumgartner M. Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton. PLoS Pathog. 2014;10:e1004003 pubmed publisher
Ratsima H, Ladouceur A, Pascariu M, Sauvé V, Salloum Z, Maddox P, et al. Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability. Proc Natl Acad Sci U S A. 2011;108:E914-23 pubmed publisher
Chiang Y, Ho K, Sun C, Chiu J, Lee F, Liao F, et al. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE. 2013;8:e61761 pubmed publisher

product information

Catalog No :

GTX20032

Product Name :

c-Myc antibody [9E10]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

200.00μg

List Price :

239 USD

list of Pubmed id :

17588950,20065654,19536328,21987786,23620790,23623971,24626571

Clone :

9E10

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [9E10] to c-Myc

CrossReactivity :

Background :

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]

Immunogen :

Synthetic peptide sequence corresponding to the C-terminal region (residues 408-439) of human c-myc conjugated to keyhole limpet hemocyanin.

Specificity :

This antibody recognizes the sequence EQKLISEEDL.

Buffer :

Phosphate buffered saline containing 0.09% Sodium Azide (NaN3)

Uses :

ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.