PCNA antibody [PC10] | GeneTex GTX20029 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

PCNA antibody [PC10]

catalog :

GTX20029

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PC10

reactivity :

fish, gilthead bream, human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

GeneTex product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; fish; 1:600; loading ...; fig 5c	Chauvigné F, Ollé J, Gonzalez W, Duncan N, Gimenez I, Cerdà J. Toward developing recombinant gonadotropin-based hormone therapies for increasing fertility in the flatfish Senegalese sole.. PLoS ONE. 2017;12:e0174387 pubmed publisher
immunohistochemistry - paraffin section; gilthead bream; 1:300; loading ...; fig s1	Boj M, Chauvigné F, Zapater C, Cerdà J. Gonadotropin-Activated Androgen-Dependent and Independent Pathways Regulate Aquaporin Expression during Teleost (Sparus aurata) Spermatogenesis. PLoS ONE. 2015;10:e0142512 pubmed publisher
	Liu Y, Bi T, Shen G, Li Z, Wu G, Wang Z, et al. Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway. Cytotechnology. 2016;68:123-33 pubmed publisher
	Rul F, Ben-Yahia L, Chegdani F, Wrzosek L, Thomas S, Noordine M, et al. Impact of the metabolic activity of Streptococcus thermophilus on the colon epithelium of gnotobiotic rats. J Biol Chem. 2011;286:10288-96 pubmed publisher
	Tomas J, Wrzosek L, Bouznad N, Bouet S, Mayeur C, Noordine M, et al. Primocolonization is associated with colonic epithelial maturation during conventionalization. FASEB J. 2013;27:645-55 pubmed publisher
	Ji R, Eshita Y, Xing L, Miura M. Multiple expressions of lymphatic markers and morphological evolution of newly formed lymphatics in lymphangioma and lymph node lymphangiogenesis. Microvasc Res. 2010;80:195-201 pubmed publisher
	Cherbuy C, Honvo-Houeto E, Bruneau A, Bridonneau C, Mayeur C, Duée P, et al. Microbiota matures colonic epithelium through a coordinated induction of cell cycle-related proteins in gnotobiotic rat. Am J Physiol Gastrointest Liver Physiol. 2010;299:G348-57 pubmed publisher
	Guo Z, Zheng L, Xu H, Dai H, Zhou M, Pascua M, et al. Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding. Nat Chem Biol. 2010;6:766-73 pubmed publisher
	Kumar R, Zhang H, Holm C, Vadlamudi R, Landberg G, Rayala S. Extranuclear coactivator signaling confers insensitivity to tamoxifen. Clin Cancer Res. 2009;15:4123-30 pubmed publisher
	Krasna L, Dudorkinova D, Vedralová J, Vesely P, Pokorna E, Kudlackova I, et al. Large expansion of morphologically heterogeneous mammary epithelial cells, including the luminal phenotype, from human breast tumours. Breast Cancer Res Treat. 2002;71:219-35 pubmed
	Turpin W, Humblot C, Noordine M, Wrzosek L, Tomas J, Mayeur C, et al. Behavior of lactobacilli isolated from fermented slurry (ben-saalga) in gnotobiotic rats. PLoS ONE. 2013;8:e57711 pubmed publisher

product information

Catalog No :

GTX20029

Product Name :

PCNA antibody [PC10]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

23118025,20466941,19470742,21239485,20382171,20729856,12002341,23577056,25037728

Clone :

PC10

Isotype :

IgG2a

Product Description :

Mouse monoclonal [PC10] to PCNA-Proliferation Marker

CrossReactivity :

Hu, Ms, Rat

Background :

PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis).

Immunogen :

Protein A-rat PCNA (proliferating cell nuclear antigen) fusion obtained from pC2T

Specificity :

Specific for PCNA p36 protein expressed at high levels in proliferating cells

Buffer :

Phosphate-buffered saline

Uses :

FACS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB, WB-Ag

Concentration :

0.5mg/ml

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

more info or order :

GeneTex product webpage