This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD3 antibody [UCHT1]
catalog :
GTX20022
quantity :
100.00μg
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, radioimmunoassay, immunohistochemistry - frozen section
citations: 1
| Reference |
|---|
Yarbrough W, Mukherjee R, Escobar G, Mingoia J, Sample J, Hendrick J, et al. Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling. Circulation. 2003;108:1753-9 pubmed
|
product information
Catalog No :
GTX20022
Product Name :
CD3 antibody [UCHT1]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
299 USD
list of Pubmed id :
12975256
Clone :
UCHT1
Isotype :
IgG1
Product Description :
Mouse monoclonal antibody [UCHT1] to CD3
CrossReactivity :
Hu, Mk, Pig, Chmp
Background :
T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
Immunogen :
Human infant thymocytes and Sezary cells
Specificity :
Detects the non-glycosylated epsilon chain of CD3 (MW 20kD) which is closely associated on the lymphocyte cell surface with the T cell antigen receptor (TCR).The antibody reacts with T cells in the thymus, bone marrow, and peripheral blood and is able to induce proliferation of mature thymocytes and T cells with, and without the presence of IL-2.The majority of T cell neoplasms are positive with this antibody.
Uses :
FACS, ICC/IF, IHC, IHC-Fr, IP, RIA
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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