product summary
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company name :
GeneTex
product type :
antibody
product name :
Ki67 antibody [SP6]
catalog :
GTX16667
quantity :
500.00μl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
GeneTex product webpage
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 6b
Liu X, Chen X, Xiao M, Zhu Y, Gong R, Liu J, et al. RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1b
Guillermin O, Angelis N, Sidor C, Ridgway R, Baulies A, Kucharska A, et al. Wnt and Src signals converge on YAP-TEAD to drive intestinal regeneration. EMBO J. 2021;40:e105770 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1d
Liu J, Cao L, Zhao N, Feng Y, Yu Z, Li Y, et al. miR‑338‑3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and β‑catenin signaling pathways. Mol Med Rep. 2019;20:33-40 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
  • immunohistochemistry - paraffin section; mouse; fig 4
Liou A, Wu S, Liao C, Chang Y, Chang C, Shih C. A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71. Sci Rep. 2016;6:31151 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 3
Murai K, Sun G, Ye P, Tian E, Yang S, Cui Q, et al. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. Nat Commun. 2016;7:10965 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Kijani S, Yrlid U, Heyden M, Levin M, Borén J, Fogelstrand P. Filter-Dense Multicolor Microscopy. PLoS ONE. 2015;10:e0119499 pubmed publisher
Przepiorski A, Vanichapol T, Espiritu E, Crunk A, Parasky E, McDaniels M, et al. Modeling oxidative injury response in human kidney organoids. Stem Cell Res Ther. 2022;13:76 pubmed publisher
Burocziova M, Burdova K, Martinikova A, Kaspárek P, Kleiblova P, Danielsen S, et al. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death Dis. 2019;10:818 pubmed publisher
Babos K, Galloway K, Kisler K, Zitting M, Li Y, Shi Y, et al. Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. Cell Stem Cell. 2019;25:486-500.e9 pubmed publisher
Wiggins K, Parry A, Cassidy L, Humphry M, Webster S, Goodall J, et al. IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype. Aging Cell. 2019;18:e12946 pubmed publisher
Lee S, Kwon S, Lee Y, Kaya P, Kim J, Ahn C, et al. Dietary intake of genistein suppresses hepatocellular carcinoma through AMPK-mediated apoptosis and anti-inflammation. BMC Cancer. 2019;19:6 pubmed publisher
Liang S, Ma H, Zhong Z, Dhar D, Liu X, Xu J, et al. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Gastroenterology. 2019;156:1156-1172.e6 pubmed publisher
Beaudry K, Langlois M, Montagne A, Cagnol S, Carrier J, Rivard N. Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis. J Cell Physiol. 2019;234:6731-6745 pubmed publisher
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle N, et al. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer Cell. 2017;32:824-839.e8 pubmed publisher
Chen S, Lu W, Yueh M, Rettenmeier E, Liu M, Paszek M, et al. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proc Natl Acad Sci U S A. 2017;114:E1432-E1440 pubmed publisher
Abraham S, Scarcia M, Bagshaw R, McMahon K, Grant G, Harvey T, et al. A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Nat Commun. 2015;6:7286 pubmed publisher
Yueh M, Taniguchi K, Chen S, Evans R, Hammock B, Karin M, et al. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci U S A. 2014;111:17200-5 pubmed publisher
Nakagawa H, Umemura A, Taniguchi K, Font Burgada J, Dhar D, Ogata H, et al. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell. 2014;26:331-343 pubmed publisher
Li K, Hua K, Lin Y, Su C, Ko J, Hsiao M, et al. Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma. Mol Cancer. 2014;13:172 pubmed publisher
Chen S, Yueh M, Bigo C, Barbier O, Wang K, Karin M, et al. Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proc Natl Acad Sci U S A. 2013;110:19143-8 pubmed publisher
Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, et al. MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways. Cancer Lett. 2013;337:226-36 pubmed publisher
Chen C, Wang S, Wei E, Chu T, Hsieh P. Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction. Mol Ther. 2013;21:670-9 pubmed publisher
Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough B, et al. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. Am J Pathol. 2013;182:180-91 pubmed publisher
Grivennikov S, Wang K, Mucida D, Stewart C, Schnabl B, Jauch D, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 2012;491:254-8 pubmed publisher
Wang C, Hsieh I, Cherng W, Chen C, Tung T, Lee J, et al. Differentiation profile of peripheral blood-derived vascular progenitor cell predicts intimal hyperplasia after coronary stenting. Heart Vessels. 2012;27:10-9 pubmed publisher
Perone M, Bertera S, Shufesky W, DiVito S, Montecalvo A, Mathers A, et al. Suppression of autoimmune diabetes by soluble galectin-1. J Immunol. 2009;182:2641-53 pubmed publisher
product information
Catalog No :
GTX16667
Product Name :
Ki67 antibody [SP6]
Host Species :
Rabbit
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
500.00μl
list of Pubmed id :
23034650,21331618,23295948,23159949,19234158,24191041,23684551,25027955,25132496,25404284,25739088
Clone :
SP6
Isotype :
IgG
Product Description :
Rabbit monoclonal [SP6] to Ki67 - Proliferation Marker
CrossReactivity :
Hu, Ms, Rat
Background :
Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67-positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki67 index and histologically low-grade tumours is strong.
Immunogen :
Synthetic peptide (Human) (C terminal).
Buffer :
Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide
Uses :
ICC/IF, IHC, IHC-Fr, IHC-P, WB
General References :
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Image Legend_4 :
Human Bladder Transitional Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_5 :
Human Esophagus stained with anti-Ki-67 antibody (GTX16667)
Image Legend_6 :
Human Fallopian Tube stained with anti-Ki-67 antibody (GTX16667)
Image Legend_7 :
Human Endometrial Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_8 :
Human Cervical Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_9 :
Human Skin Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_10 :
Human Hepatocellular Carcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_11 :
Human Lung Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_12 :
Human Stomach Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_13 :
Human Skin stained with anti-Ki-67 antibody (GTX16667)
Image Legend_14 :
Human Thymus stained with anti-Ki-67 antibody (GTX16667)
Image Legend_15 :
Human Spleen stained with anti-Ki-67 antibody (GTX16667)
Image Legend_16 :
Human Spinal Cord stained with anti-Ki-67 antibody (GTX16667)
Image Legend_17 :
Human Stomach stained with anti-Ki-67 antibody (GTX16667)
Image Legend_18 :
Human Liver stained with anti-Ki-67 antibody (GTX16667)
Image Legend_19 :
Human Prostate stained with anti-Ki-67 antibody (GTX16667)
Image Legend_20 :
Human Lung stained with anti-Ki-67 antibody (GTX16667)
Image Legend_21 :
Human Lung Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_22 :
Human Lymph Node stained with anti-Ki-67 antibody (GTX16667)
Image Legend_23 :
Human Prostate Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_24 :
Human Testis stained with anti-Ki-67 antibody (GTX16667)
Image Legend_25 :
Human B Cell Lymphoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_26 :
Human Thyroid stained with anti-Ki-67 antibody (GTX16667)
Image Legend_27 :
Human HK Lymphoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_28 :
Human Colon stained with anti-Ki-67 antibody (GTX16667)
Image Legend_29 :
Human Colon Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
Image Legend_30 :
Human Breast stained with anti-Ki-67 antibody (GTX16667)
Image Legend_31 :
Human Breast Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
more info or order :
GeneTex product webpage
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA