This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
ATM (phospho Ser1981) antibody [10H11]
catalog :
GTX15666
quantity :
100.00μg
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
10H11
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
product information
Catalog No :
GTX15666
Product Name :
ATM (phospho Ser1981) antibody [10H11]
Host Species :
Mouse
Clonality :
Monoclonal
Antigen Modification :
Phosphorylated
Product Type :
Primary antibody
Size :
100.00μg
List Price :
289 USD
Clone :
10H11
Isotype :
IgG1
Product Description :
Mouse monoclonal antibody [10H11] to S1981-phosphorylated ATM
CrossReactivity :
Hu, Ms
Background :
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
Immunogen :
Synthetic peptide corresponding to residues S(1974) L A F E E S(p) Q S T T I S S(1988) of human ATM Kinase protein.
Buffer :
PBS containing 1 mg/ml BSA and 0.05 % sodium azide
Uses :
ICC/IF, IP, WB
General References :
-20° C, Avoid Freeze/Thaw Cycles
company information
GeneTex
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