C Reactive Protein antibody | GeneTex GTX14008 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

C Reactive Protein antibody

catalog :

GTX14008

quantity :

50.00μg

price :

289 USD

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Catalog No :

GTX14008

Product Name :

C Reactive Protein antibody

Host Species :

Chicken

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

50.00μg

List Price :

289 USD

Isotype :

IgY

Product Description :

Chicken polyclonal to C Reactive Protein

CrossReactivity :

Background :

C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C-reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rapture.

Immunogen :

Full length native protein(Human).

Buffer :

Preservative: NoneConstituents: PBS

Uses :

ELISA, WB

Concentration :

1mg/ml