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product summary
company name :
GeneTex
product type :
antibody
product name :
Fas antibody
catalog :
GTX13550
quantity :
100.00μg
price :
359 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, FACS
citations: 1
product information
Catalog No :
GTX13550
Product Name :
Fas antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
359 USD
list of Pubmed id :
21227512
Isotype :
IgG
Product Description :
Rabbit Polyclonal antibody to Fas
CrossReactivity :
Hu, Ms, Dog, Rat
Background :
CD95, also known as FAS or APO-1, is a 36 kDa cell surface type I- membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. CD95 is a member of the TNF receptor family, which includes TNFR-1, TNFR-2, CD27, CD30 and CD40. Binding of CD95 Ligand to CD95 or crosslinking of CD95 by anti-CD95 monoclonal antibodies leads to apoptosis of CD95 expressing cells. CD95 belongs to a subgroup of family members that have a death domain (DD) which contains 70 amino acids near the carboxyl-terminal region of the molecule. The binding of adaptor molecules to this DD is responsible for transmitting the death signal for apoptosis. Stimulation of CD95 results in aggregation of its DD, leading to the recruitment of FADD and caspase-8 that together with the receptor form the death-inducing signaling complex (DISC).
Immunogen :
Synthetic peptide: ESLKLRRRVHETDKNC conjugated to KLH, corresponding to amino acids 29-44 of Mouse CD95 .
Buffer :
Preservative: 0.09% Sodium Azide; Constituents: PBS. pH 7.2
Uses :
FACS, IHC, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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