This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD40 antibody
catalog :
GTX13545
quantity :
50.00μl
price :
259 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot
product information
Catalog No :
GTX13545
Product Name :
CD40 antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
50.00μl
List Price :
259 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to CD40
CrossReactivity :
Hu, Ms, Dog, Mk, Pig, Rat, Gpig, Hm, Rb, Shp
Background :
CD40 (48 to 50 kDa) is a transmembrane glycoprotein mainly expressed on the surface of B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions, central to the control of thymus dependent humoral immunity and may be critical in the development of cell mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
Immunogen :
Synthetic peptide: CQPVTQEDGKESRISVQERQ conjugated to KLH, corresponding to amino acids 258-277 of Human CD40.
Specificity :
The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
Buffer :
PBS containing 50% glycerol and 0.09% sodium azide
Uses :
WB
Concentration :
1 mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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