SOD2 antibody | GeneTex GTX13533 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

SOD2 antibody

catalog :

GTX13533

quantity :

50.00μg

price :

299 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

western blot, immunohistochemistry, immunoprecipitation, enzyme immunoassay

citations: 1

Reference
Chen Y, Chou H, Lin S, Chen Y, Chang Y, Chen L, et al. Cardioprotective Effects of Quercetin in Cardiomyocyte under Ischemia/Reperfusion Injury. Evid Based Complement Alternat Med. 2013;2013:364519 pubmed publisher

product information

Catalog No :

GTX13533

Product Name :

SOD2 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

50.00μg

List Price :

299 USD

list of Pubmed id :

23573126

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to SOD2

CrossReactivity :

Hu, Ms, Cow, Dog, Mk, Pig, Rat, Hm, Rb, Shp, Xl

Background :

Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells. They are: extracellular SOD (EC SOD), copper and zinc-containing SOD (Cu/Zn SOD) and manganese-containing SOD (Mn SOD). The Cu/Zn form contains Cu and Zn ions and exists as a 32 kDa dimer in the cytosol. Mn SOD is an 80 kDa tetramer that contains Mn ion and resides in the mitochondrial matrix. Mn SOD is a tumor necrosis factor (TNF)-inducible enzyme that protects cells from TNF-mediated apoptosis via superoxide anion detoxification and the subsequent regulation of apoptosis through cytochrome c release and the modulation of the redox state of the mitochondria. Mn SOD has also been shown to be a tumor suppressor in human breast cancer. Overexpression of this enzyme protects neurons from NMDA- and nitric oxide-induced neurotoxicity.

Immunogen :

Full length protein (Human).

Buffer :

50% Glycerol, 50mM Sodium Phosphate. pH 7.2 containing 0.1%BSA and 0.1% Sodium Azide

Uses :

EIA, IHC, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.