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product summary
company name :
GeneTex
product type :
antibody
product name :
SOD1 antibody
catalog :
GTX13499
quantity :
50.00μg
price :
289 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, ELISA, immunohistochemistry
citations: 1
product information
Catalog No :
GTX13499
Product Name :
SOD1 antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
50.00μg
List Price :
289 USD
list of Pubmed id :
24726403
Isotype :
IgG
Product Description :
Rabbit polyclonal to Cu / Zn SOD
CrossReactivity :
Hu, Ms, Cow, Dog, Mk, Pig, Rat, Hm, Rb, Shp, Xl
Background :
Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells. They are: extracellular SOD (EC SOD), copper and zinc-containing SOD (CuZn SOD) and manganese-containing SOD (Mn SOD). The CuZn form contains Cu and Zn ions and exists as a 32 kDa dimer in the cytosol. Mn SOD is an 80 kDa tetramer that contains Mn ion and resides in the mitochondrial matrix. Mn SOD is a tumor necrosis factor (TNF)- inducible enzyme that protects cells from TNF-mediated apoptosis via superoxide anion detoxification and the subsequent regulation of apoptosis through cytochrome c release and the modulation of the redox state of the mitochondria. Mn SOD has also been shown to be a tumor suppressor in human breast cancer. Overexpression of this enzyme protects neurons from NMDA- and nitric oxide-induced neurotoxicity.
Immunogen :
Full length protein (Rat).
Buffer :
Preservative: 0.1% Sodium Azide; Constituents: 50% Glycerol, 0.1M Sodium Phosphate. pH 7.0
Uses :
ELISA, IHC, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
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