| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 4d
| Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 3a
| Kurelac I, Iommarini L, Vatrinet R, Amato L, De Luise M, Leone G, et al. Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. Nat Commun. 2019;10:903 pubmed publisher |
- western blot; human; fig 2e
| Di K, Lomeli N, Wood S, Vanderwal C, Bota D. Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma. Oncotarget. 2016;7:77457-77467 pubmed publisher |
- western blot; mouse; fig 5
- chromatin immunoprecipitation; human; fig 2
- western blot; human; fig 2
| Tsai S, Huang P, Hsu Y, Peng Y, Lee C, Wang J, et al. Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep. 2016;6:28612 pubmed publisher |
- western blot; mouse; fig 5
| Kudová J, Prochazkova J, Vašíček O, Perecko T, Sedláčková M, Pesl M, et al. HIF-1alpha Deficiency Attenuates the Cardiomyogenesis of Mouse Embryonic Stem Cells. PLoS ONE. 2016;11:e0158358 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s10e
| Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed publisher |
- western blot; human; 1:800; fig s1
| Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed publisher |
| Chan C, Wu C, Dubey N, Wei H, Lu J, Mao S, et al. Modulating redox homeostasis and cellular reprogramming through inhibited methylenetetrahydrofolate dehydrogenase 2 enzymatic activities in lung cancer. Aging (Albany NY). 2020;12:17930-17947 pubmed publisher |
| Pan C, Chen C, Shih C, Wang M, Wang J, Wu C. Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta. Aging (Albany NY). 2019;11:8085-8102 pubmed publisher |
| Terasaki M, Ogawa Y, Endo T, Maeda H, Hamada J, Osada K, et al. Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia. Anticancer Res. 2018;38:2169-2179 pubmed |
| Kuang Y, Han X, Xu M, Yang Q. Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis. Cancer Med. 2018;7:1416-1429 pubmed publisher |
| Kuriyama S, Tsuji T, Sakuma T, Yamamoto T, Tanaka M. PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer. Cell Death Discov. 2018;4:11 pubmed publisher |
| Owada S, Endo H, Shida Y, Okada C, Ito K, Nezu T, et al. Autophagy?mediated adaptation of hepatocellular carcinoma cells to hypoxia?mimicking conditions constitutes an attractive therapeutic target. Oncol Rep. 2018;39:1805-1812 pubmed publisher |
| Lee S, Park H, Yang Y, Lee E, Kim J, Khang G, et al. Improvement of islet function and survival by integration of perfluorodecalin into microcapsules in vivo and in vitro. J Tissue Eng Regen Med. 2018;12:e2110-e2122 pubmed publisher |
| Bunai K, Okubo H, Hano K, Inoue K, Kito Y, Saigo C, et al. TMEM207 hinders the tumour suppressor function of WWOX in oral squamous cell carcinoma. J Cell Mol Med. 2018;22:1026-1033 pubmed publisher |
| Kitajima S, Lee K, Hikasa H, Sun W, Huang R, Yang H, et al. Hypoxia-inducible factor-1? promotes cell survival during ammonia stress response in ovarian cancer stem-like cells. Oncotarget. 2017;8:114481-114494 pubmed publisher |
| Li S, Takahara T, Fujino M, Fukuhara Y, Sugiyama T, Li X, et al. Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice. PLoS ONE. 2017;12:e0187810 pubmed publisher |
| Zera K, Zastre J. Thiamine deficiency activates hypoxia inducible factor-1? to facilitate pro-apoptotic responses in mouse primary astrocytes. PLoS ONE. 2017;12:e0186707 pubmed publisher |
| Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Fang S, et al. ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling. Cancer Res. 2017;77:5831-5845 pubmed publisher |
| Owada S, Ito K, Endo H, Shida Y, Okada C, Nezu T, et al. An Adaptation System to Avoid Apoptosis via Autophagy Under Hypoxic Conditions in Pancreatic Cancer Cells. Anticancer Res. 2017;37:4927-4934 pubmed |
| Kraus R, Yu X, Cordes B, Sathiamoorthi S, Iempridee T, Nawandar D, et al. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PLoS Pathog. 2017;13:e1006404 pubmed publisher |
| Ji Y, Yang C, Tang Z, Yang Y, Tian Y, Yao H, et al. Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. Nat Commun. 2017;8:15308 pubmed publisher |
| Tsai T, Yu C, Chang Y, Lin Y, Huang C, Kuo Y, et al. Protective Effect of Caffeic Acid Derivatives on tert-Butyl Hydroperoxide-Induced Oxidative Hepato-Toxicity and Mitochondrial Dysfunction in HepG2 Cells. Molecules. 2017;22: pubmed publisher |
| Wang L, Chiou S, Chai C, Hsi E, Chiang C, Huang S, et al. Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Oncogene. 2017;36:4405-4414 pubmed publisher |
| Laubenthal L, Ruda L, Sultana N, Winkler J, Rehage J, Meyer U, et al. Effect of increasing body condition on oxidative stress and mitochondrial biogenesis in subcutaneous adipose tissue depot of nonlactating dairy cows. J Dairy Sci. 2017;100:4976-4986 pubmed publisher |
| Fujiki K, Inamura H, Miyayama T, Matsuoka M. Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. J Biol Chem. 2017;292:7942-7953 pubmed publisher |
| Lin Y, Chao T, Yeh C, Roffler S, Kannagi R, Yang R. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis. Arterioscler Thromb Vasc Biol. 2017;37:144-155 pubmed publisher |
| Barnes E, Chen C, Sedan O, Cornfield D. Loss of smooth muscle cell hypoxia inducible factor-1? underlies increased vascular contractility in pulmonary hypertension. FASEB J. 2017;31:650-662 pubmed publisher |
| Chuang M, Chang J, Hsu L, Jan M, Lu F. Antitumor Activity of the Chinese Medicine JC-001 Is Mediated by Immunomodulation in a Murine Model of Hepatocellular Carcinoma. Integr Cancer Ther. 2017;16:516-525 pubmed publisher |
| Wong M, Kantores C, Ivanovska J, Jain A, Jankov R. Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling. Am J Physiol Lung Cell Mol Physiol. 2016;311:L985-L999 pubmed publisher |
| Chiang C, Chu P, Hou M, Hung W. MiR-182 promotes proliferation and invasion and elevates the HIF-1?-VEGF-A axis in breast cancer cells by targeting FBXW7. Am J Cancer Res. 2016;6:1785-98 pubmed |
| Kudová J, Vašíček O, Ciz M, Kubala L. Melatonin promotes cardiomyogenesis of embryonic stem cells via inhibition of HIF-1? stabilization. J Pineal Res. 2016;61:493-503 pubmed publisher |
| Lin H, Liu S, Yen E, Li T, Lai I. microRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1. Antioxid Redox Signal. 2017;26:583-597 pubmed publisher |
| Jou Y, Tsai Y, Lin C, Tung C, Shen C, Tsai H, et al. Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation. Oncotarget. 2016;7:65403-65417 pubmed publisher |
| Logsdon D, Grimard M, Luo M, Shahda S, Jiang Y, Tong Y, et al. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models. Mol Cancer Ther. 2016;15:2722-2732 pubmed |
| Lim N, Sham A, Chee S, Chan C, Raghunath M. Combination of ciclopirox olamine and sphingosine-1-phosphate as granulation enhancer in diabetic wounds. Wound Repair Regen. 2016;24:795-809 pubmed publisher |
| Hiromura M, Mori Y, Kohashi K, Terasaki M, Shinmura K, Negoro T, et al. Suppressive Effects of Glucose-Dependent Insulinotropic Polypeptide on Cardiac Hypertrophy and Fibrosis in Angiotensin II-Infused Mouse Models. Circ J. 2016;80:1988-97 pubmed publisher |
| Lin C, Lee H, Lee M, Pan S, Ke C, Chiu A, et al. Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma. Int J Mol Sci. 2016;17: pubmed publisher |
| Erapaneedi R, Belousov V, Schäfers M, Kiefer F. A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. EMBO J. 2016;35:102-13 pubmed publisher |
