This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
c-Jun antibody
catalog :
GTX11914
quantity :
50.00μl
price :
269 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot
product information
Catalog No :
GTX11914
Product Name :
c-Jun antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
50.00μl
List Price :
269 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to c - Jun
CrossReactivity :
Hu, Ms, Cow, Mk, Pig, Rat, Shp
Background :
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. c-Jun (previously known as the Fos-binding protein p39) and c-Fos form a complex in the nucleus. AP 1 (activating protein-1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto-oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Immunogen :
Synthetic peptide: PSESGPYGYSNPKILKQS, corresponding to amino acids 20-37 of Human c-Jun
Buffer :
Phosphate-buffered saline containing 0.2% gelatin, 0.01% thiomerosal, and 0.1% sodium azide
Uses :
WB
Concentration :
0.2mg/ml
General References :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA